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Innovations in Exercise Research — Completed Projects

Leading-edge research projects completed by the physicians and scientists at the UC Irvine Health Pediatric Exercise and Genomics Research Center (PERC) include:

  • Impact of exercise training on children with neural tube defects: An exploratory study. Lead researchers: Shlomit Radom-Aizik, PhD; Dan M. Cooper, MD, and Kimberly BeDell, MD, medical director of pediatric rehabilitation at Miller Children's and Women's Hospital Long Beach. In collaboration with Melissa D'Eloia, PhD, of the Department of Recreation and Leisure Studies at Cal State University, Long Beach; Robert Arnhold, PhD, coordinator of the Adapted Physical Activity Program and director of the Center on Disability and Health at Slippery Rock University of Pennsylvania.

  • DNA methylation is altered in human skeletal muscle in response to exercise training. Lead researchers: Gregory R. Adams, PhD, Shlomit Radom-Aizik, PhD, and Fadia Haddad, PhD, in collaboration with Dr. Eric Hoffman, Children's National Medical Center, George Washington University, Washington, D.C.

  • The effect of an Ironman Triathlon on the immune system genomic response. Lead researcher: Shlomit Radom-Aizik, PhD, in collaboration with the University of Connecticut, Storrs.

  • Exercise testing in children: Definitions, data harmonization and translational research. Lead researcher: Dan M. Cooper, MD.
  • Exercise and blood biomarkers in obese children. Lead researcher: Pietro Galassetti, MD, PhD.